ET, Jurickson Profar and the San Diego Padres (88-66) face Andrew Vaughn and the Chicago White Sox (36-118) at PETCO Park.

San Diego Padres manager Mike Shildt has defended closer Robert Suarez lately but the question must be asked: Does a likely playoff-bound team with World Series dreams have a serious question to ...

Lenyn Sosa hit a tying two-run homer with two outs in the ninth inning, but the Chicago White Sox lost their 118th game when ...

The Chicago White Sox (36-118) bring a three-game losing streak into a road contest against the San Diego Padres (88-66) at 8 ...

The Chicago White Sox staged a two-out rally in the 9th but fell to the San Diego Padres 3-2 in 10 on Friday. The Sox are ...

What to look for from the top San Diego Padres and Chicago White Sox players and how to watch the game as they face off on ...

Manny Machado and the San Diego Padres square off against the Chicago White Sox and starter Chris Flexen on Saturday at 8:40 ...

The San Diego Padres (88-66) take on the Chicago White Sox (36-118), who will be trying to halt a three-game losing streak, ...

BOTTOM LINE: The Chicago White Sox, on a three-game losing streak, take on the San Diego Padres. San Diego is 43-36 in home games and 88-66 overall. The Padres have a 37-20 record in games when they ...

Fernando Tatis Jr. ripped an RBI double in the bottom of the 10th inning Friday night as the San Diego Padres nipped the ...

Preview the Sept. 21 matchup between the San Diego Padres and Chicago White Sox with odds over/under, game spread, betting ...

Oddsmakers have listed player props for Jurickson Profar, Andrew Vaughn and others when the San Diego Padres host the Chicago ...