It's only Week 3, but both the 49ers and Rams are dealing with several key injuries entering Sunday's game. For San Francisco ...

Greg Scholz runs through the biggest fantasy football injury worries of Week 3, leading off with A.J. Brown's precarious ...

Samuel (calf) has been ruled out for Sunday's game against the Rams, Matt Barrows of The Athletic reports.

Brock Purdy plays much better with Deebo Samuel than without him. That's a fact. This Sunday, Purdy and the 49ers will have ...

Speaking to NBC Sports Bay Area's Greg Papa on "49ers Game Plan," Kyle Shanahan explained why the offense won't change ...

San Francisco 49ers' George Kittle is listed as doubtful for Sunday's game against the Rams. He joins Christian McCaffrey and ...

Sunday’s NFC West showdown between the San Francisco 49ers and Los Angeles Rams could be an ugly affair, as both teams are ...

San Francisco 49ers head coach Kyle Shanahan joined Bay Area radio station KNBR on Thursday to provide an update on two ...

The San Francisco 49ers will likely be without All-Pro tight end George Kittle for Sunday's game against the Los Angeles Rams ...

San Francisco 49ers quarterback Brock Purdy will be tested in the coming weeks with the absence of key offensive weapons.

The San Francisco 49ers are officially listing tight end George Kittle as doubtful to play for their Week 3 divisional ...

The Minnesota Vikings will be without wide receiver Jordan Addison on Sunday when they host the San Francisco 49ers at U.S.